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4415 Euclid Ave Cleveland, OH 44103 216.361.5411
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Fledderus J., Thienen J., Boon R., Dekker R., Rohlena J., Volger O., Bijnens A., Daemen M., Kuiper J., Berkel T., Pannekoek H., Horrevoets A., Prolonged shear stress and KLF2 suppress constitutive proinflammatory transcription through inhibition of ATF2. Blood First Edition Paper 2007 JAN, 1-38.
CUCULLO L., HOSSAIN M., RAPP E., MANDERS T., MARCHI N., AND JANIGRO D., Development of a Humanized In Vitro Blood–Brain Barrier Model to Screen for Brain Penetration of Antiepileptic Drugs. Epilepsia, 2007 MAR, 48(3):505–516.
SANTAGUIDA S., JANIGRO D., HOSSAIN M., OBY M., RAPP E. AND CUCULLO L., Side by side comparison between dynamic versus static models of blood-brain barrier in vitro: a permeability study. Brain Res, 2006 Sep 13;1109(1):1-13.
CUCULLO L., WEKSLER B., COURAUD P-O., HOSSAIN M, RAPP E., MANDERS T., AND JANIGRO D., Immortalized human brain endothelial cells and flow-based vascular modeling: a marriage of convenience for rational neurovascular studies. Journal of Cerebral Blood Flow & Metabolism, 2007;1-17.
STANNESS, K.A., WESTRUM, L.E., MASCAGNI, P., FORNACIARI, E., NELSON, J.A., STENGLEIN, S.G., JANIGRO, D. Morphological and Functional Characterization of an In Vitro Blood-brain Barrier Model. J. Cerebral Blood Flow Metab, 2008 Feb;28(2):312-28.
PEKNY, M., STANNESS, K.A., ELIASSON, C., BETSHOLTZ, C., JANIGRO, D. Impaired induction of blood-brain barrier properties in aortic endothelial cells by astrocytes from GFAP-deficient mice. Glia, 22, 1-11, (1997).
JANIGRO, D., STRELOW, L., GRANT, G.A. and NELSON, J.A. Development of an in vitro blood-brain barrier model for neuro-AIDS, NEURO-AIDS, Vol. 1 (4) (1998).
GRANT, G.A., ABBOTT, N.J., JANIGRO, D. Understanding the Physiology of the Blood-Brain Barrier: in vitro Models, News in Physiological Sciences, Vol. 14, Nov. (1998).
STANNESS, K.A., NEUMAIER, J.F., SEXTON, T.J., GRANT, G.A., ADRIANA EMMI, MARIS, D.O. and JANIGRO, D. A new model of the blood-brain barrier: co-culture of neuronal, endothelial and glial cells under dynamic conditions, Neuroreport, 10(18) 3725-3731, (1999).
JANIGRO, D., LEAMAN, S. and STANNESS, K.A. Dynamic in vitro modeling of the BBB: an novel tool for the studies of drug delivery to the brain, Pharmacological Science and Technology Today, 2(1) 7-12, (1999).
McALLISTER, M.S., KRIZANAC-BENGEZ, L, MACCHIA, F., NAFTALIN, R.J., PEDLEY, K.C., MARRONI, M., LEAMAN, S., STANNESS, K.A., JANIGRO,D.
Mechanisms of glucose transport at the blood-brain barrier: an in vitro study. Brain Research, 409, 20-30 (2000).
SALVETTI, F, CECCHETTI, P., JANIGRO, D., LUCACCHINI, A., BENZI, L and MARTINI, C. Insulin permeability across an in vitro dynamic model of endothelium, Pharmaceutical Research, 19 (2002) 445-450 (2001).
CUCULLO, L., McALLISTER, M., KIGHT, K., KRIZANAC-BENGEZ, L., MARRONI, M., MAYBERG, M., STANNESS, K., and JANIGRO, D. A new dynamic in vitro model for the multidimensional study of astrocyte-endothelial cell interactions at the blood-brain barrier, Brain Res., 951, 243 (2002).
PARKINSON, F.E., FRIESEN, J., KRIZANAC-BENGEZ, L. and JANIGRO, D. Use of a three-dimensional in vitro model of the rat blood-brain barrier to assay nucleoside efflux from brain, Brain Res., 980, 233-242 (2003).
CUCULLO, L., AUMAYR, B., RAPP, E. AND JANIGRO, D., Drug delivery and in vitro models of the blood-brain barrier, Current Opinion in Drug Discovery & Development, 8(1):88-99 (2005).
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