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4415 Euclid Ave
Cleveland, OH 44103

216.361.5411

 

Flocel


Every year millions of dollars are spent by pharmaceutical companies to develop and test drugs using in vitro models of the Blood-Brain Barrier (BBB), many of which end up not working in vivo. CleveMed has licensed technology from The Cleveland Clinic Foundation and formed Flocel Inc., to manufacture and market a practical in vitro model that more accurately reflects the BBB characteristics.

Benefits

· Matches volume ratio found in vivo

· Able to use real human cells

· Smaller cartridges reduce the number of cells required

· TEER measurements are easily made

· More accurate pharmacokinetic and toxicological studies

· One-time use, which mean no rebuilding the cartridge

· Cost effective

· Culture cells in dynamic conditions that mimic the brain

· Capable of culturing and sustaining viable stem cells


 



For decades, scientists have been trying to develop methods of testing the effects of drugs on the brain that is both safe and cost-effective. Find out more...



Flocel has developed a different model of the blood-brain barrier, DIV-BBB respects the anatomical aspects of the in situ endothelial cell-astrocyte interactions Find out more...

Researchers


Researchers
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To find out about our founders, click here

 


 


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