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Flocel

Every year millions of dollars are spent by pharmaceutical companies to develop and test drugs using in vitro models of the Blood-Brain Barrier (BBB), many of which end up not working in vivo. CleveMed has licensed technology from The Cleveland Clinic Foundation and formed Flocel Inc., to manufacture and market a practical in vitro model that more accurately reflects the BBB characteristics.

Benefits
  • Matches volume ratio found in vivo
  • Can use real human cells
  • Reduces the number of cells required
  • TEER measurements are easily made
  • More accurate pharmacokinetic and toxicological studies
  • One-time use, no rebuilding the cartridge
  • Cost effective





  • For decades, scientists have been trying to develop methods of testing the effects of drugs on the brain that is both safe and cost-effective. Find out more...


    Flocel has developed a different model of the blood-brain barrier, DIV-BBB respects the anatomical aspects of the in situ endothelial cell-astrocyte interactions Find out more...
    Researchers

    Researchers
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    To find out about our founders, click here


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